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Sodium gluconate has been synthesized by bismuth-promoted Pd/C catalyst [13]. PdCl2 to Bi(NO)3·5H2O weight ratio of 1–3 during catalyst preparation was found to be the most desirable for best promotion effect. Reaction time reduced and Bi hindered Pd/C deactivation in comparison with other noble metal catalyst.
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The present work is an attempt to study the partial oxidation of glucose in a three-phase stirred slurry reactor. Glucose is oxidized to gluconic acid and subsequently to sodium gluconate on addition of sodium hydroxide. A three-phase slurry reactor was fabricated and the reaction carried out by bubbling air through the glucose solution in the presence of Cr2O3/Al2O3 catalyst, adding NaOH and hydrogen peroxide at a pH between 9 and 10