RXMARINE CHEMICAL TAG::
Description::
Application::
HATU(1-[Bis(dimethylamino)methylene]-1H-1,2,3-triazolo[4,5-b]pyridinium 3-oxid hexafluorophosphate) is a reagent used inpeptide couplingchemistry to generate an active ester from a carboxylic acid. HATU can be used along with Hünig's base(N,N-diisopropylethylamine, DIPEA) to form amide bonds.
Technical Specifications::
Dose::
A mide bonds are one of the underpinning linkages in all living systems and are fundamental within drug discovery.
Product remark::
Industrial Usages::
Useful Area::
Related Information::
Current methods towards their synthesis frequently rely on the use of dipolar aprotic solvents; however, due to increasingly stringent regulations and growing societal pressures, safe and more sustainable alternatives are highly sought after.