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Glycine is a non-polar, hydrophobic, non-essential αamino acid. It is the simplest and smallest amino acid among all the amino acids and is chemically neutral in nature. It is used as a component of many animal and insect cell culture media. Some major functions of Glycine in cell culture involve synthesis of proteins in the cells. Hence it is also called proteinogenic amino acid. It also contributes towards cellular purine synthesis.