Product Notes
- 7921001 reads
A library of 1,3,5-trisubstituted pyrazoles was synthesized in excellent yields from the reaction of aldehyde, phenylhydrazine and alkynes in the presence of iodine via an eco-friendly, simple process performed in aqueous medium. This single pot transformation generates new C![[double bond, length as m-dash]](https://www.rsc.org/images/entities/char_e001.gif)
N, C–C, C–N bonds and proceeds by a domino reaction involving the formation of Schiff base, Mannich addition and finally intramolecular cyclisation.
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